PET-MRI: A review of challenges and solutions in the development of integrated multimodality imaging

    Publication Date
    Source Authors
    Source Title
    Source Issue
    Publication Date

    2017

    Source Authors

    • Stefaan Vandenberghe,
    • Paul K Marsden

    Source Title

    PET-MRI: A review of challenges and solutions in the development of integrated multimodality imaging

    Source Issue

    Physics in Medicine and Biology

    Volume 60, Number 4

    Page Range: 115-154


    L’articolo si colloca nel contesto scientifico della diagnostica per immagini, in particolar modo pone l’attenzione sull’importanza di determinati studi che attualmente vengo eseguiti. Negli ultimi tempi si parla di imaging ibrido o multimodale: i macchinari per la PET infatti eseguono PET e MRI, perché la PET è appunto un esame funzionale e quindi non fornisce un’idea dell’anatomia esatta della lesione o dell’alterazione che possiamo localizzare, mentre la MRI è una metodica che ci dà una valutazione peculiare e precisa dell’anatomia e dunque la PET-MRI ci consente di avere a disposizione il meglio delle due metodiche.
    L’ imaging Ibrido o Multimodale grazie all’evoluzione tecnologica sta acquisendo sempre più una maggiore prominenza nella valutazione delle principali patologie. L’originalità di questo documento offre una panoramica dei diversi sviluppi e dei problemi tecnici associati alla combinazione di PET e risonanza magnetica in un unico sistema. Dopodiché si passa ad un background teorico che illustra i diversi concetti dei rivelatori per integrare PET-MRI e minimizzare le interferenze, in seguito vengono descritti i limiti e i vantaggi delle diverse soluzioni per il rivelatore e il sistema per i sistemi di imaging preclinico e clinico. L’innovazione tecnologica ha portato alla creazione di diversi sistemi integrati PET-MRI che vengono illustrati in dettaglio nel suddetto articolo, e permettono di superare i limiti di tale tecnica permettendo di avere dei tempi più brevi, una maggiore risoluzione delle sequenze. Oltre ai concetti del rivelatore e all’integrazione del sistema, in questa revisione topica vengono discusse anche le sfide e le soluzioni proposte per la correzione dell’attenuazione e il potenziale per la correzione del movimento e il ripristino della risoluzione. L’articolo viene suddiviso in tre parti principali. La prima parte introduce la PET-MRI e ne evidenzia le proprie caratteristiche. La seconda parte entra nel dettaglio nella spiegazione delle innovazioni introdotte e della tecnica dell’esecuzione di un esame PET-MRI e le proprie caratteristiche tecniche. Al termine giungono le considerazioni finali e la validità di tale metodica Ibrida o Multimodale.

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